Small-Scale Synthesis
Cyanta's staff performs small-scale custom synthesis for discovery and preclinical needs. Our team has experience synthesizing various chemical compounds:
- Pharmaceutical APIs
- Steroids, opiates, nucleotides, indoles, quinones, anthraquinones and nitroxides
- Unnatural amino acids, thiols and phosphines
- Contrast agents and macrocylic host-guest compounds
- Heterocycles (N,O,S), organophosphorous and organosilicon compounds
- Polymers
We additionally have experience with the following chemistries:
- Oxidation (Cl02, Swern, periodate, Cr, oxygen and ozone, Dess-Martin, peroxides, Hg)
- Carbanion (Li, Mg, Mn) and Organometallic (Sn, Ge, Pd, Cu, Pt, Ru, Rh, Os)
- Reduction (hydride, dissolving metal), Hydrogenation/Hydrogenolysis (Pd, Pt, Rosenmund, RaNi)
- Halogenation (SOX2, X2, NXS, PX3) and Dehydrohalogenation
- Condensation, Hydrolysis, Amination and Esterification